Hepatic iron overload is associated with hepatocyte apoptosis during Clonorchis sinensis infection

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Hepatic iron overload is associated with hepatocyte apoptosis during Clonorchis sinensis infection

BACKGROUND Hepatic iron overload has been implicated in many liver diseases; however, whether it is involved in clonorchiasis remains unknown. The purpose of this study is to investigate whether Clonorchis sinensis (C. sinensis) infection causes hepatic iron overload, analyze the relationship between the iron overload and associated cell apoptosis, so as to determine the role of excess iron pla...

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Acute cholecystitis associated with Clonorchis sinensis infection

Clonorchis sinensis is one of the most common causes of trematodiasis that is caused by the ingestion of raw fish contaminated with infective cysts. The adult flukes are predominantly present in the intrahepatic bile ducts, but occasionally they may be found in the pancreatic duct and extrahepatic bile ducts. The clinical manifestations depend on the number of flukes, the period of infestation,...

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Dysregulation of hepatic microRNA expression profiles with Clonorchis sinensis infection

BACKGROUND Clonorchiasis remains an important zoonotic parasitic disease worldwide. The molecular mechanisms of host-parasite interaction are not fully understood. Non-coding microRNAs (miRNAs) are considered to be key regulators in parasitic diseases. The regulation of miRNAs and host micro-environment may be involved in clonorchiasis, and require further investigation. METHODS MiRNA microar...

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ژورنال

عنوان ژورنال: BMC Infectious Diseases

سال: 2017

ISSN: 1471-2334

DOI: 10.1186/s12879-017-2630-3